Adoption of the Q transcriptional regulatory system for zebrafish transgenesis
نویسندگان
چکیده
منابع مشابه
Adoption of the Q transcriptional regulatory system for zebrafish transgenesis.
The Gal4-UAS regulatory system of yeast is widely used to modulate gene expression in Drosophila; however, there are limitations to its usefulness in transgenic zebrafish, owing to progressive methylation and silencing of the CpG-rich multicopy upstream activation sequence. Although a modified, less repetitive UAS construct may overcome this problem, it is highly desirable to have additional tr...
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ژورنال
عنوان ژورنال: Methods
سال: 2014
ISSN: 1046-2023
DOI: 10.1016/j.ymeth.2013.06.012